The purpose of this study is to compare the safety and effectiveness of two drug-eluting stents in the treatment of coronary artery disease: the SYNERGYTM Everolimus-Eluting Platinum Chromium Coronary Stent System (SYNERGY stent) and the PROMUS Element™ Plus Everolimus Eluting Platinum Chromium Coronary Stent System (PROMUS Element Plus stent).
The SYNERGY stent is investigational, while the PROMUS stent has been approved by the FDA.
The SYNERGY and PROMUS Element Plus stents are different in the location and type of the coating (polymer) used on the metal. The polymer holds the drug onto the stent. The polymer on the SYNERGY stent is on the outside of the stent (side touching the artery wall), whereas, the polymer on the PROMUS Element Plus stent is on all sides of the stent (the inside and outside of the stent). Additionally, the polymer on the SYNERGY stent is bioabsorbable. It is completely absorbed by your body within 4 months. The polymer on the PROMUS Element Plus stent is not absorbed by your body and remains permanently on the stent.