Prostate Cancer: A031201 (Iowa Cancer Specialists)

Alliance A031201: Phase III Trial of Enzalutamide (NSC #766085) Versus Enzalutamide, Abiraterone and Prednisone for Castration Resistant Metastatic Prostate Cancer

Objective

The purpose of this study is to compare the effects, good and/or bad, of abiraterone, prednisone, and enzalutamide with enzalutamide alone on patients that have prostate cancer that has spread and has not responded to hormonal therapy to find out which is better.

Doctors are uncertain about what is the best way to treat castration resistant prostate cancer (CRPC). In this study, patients will get either the combination of abiraterone, prednisone, and enzalutamide or enzalutamide alone.

Abiraterone and enzalutamide are both hormonal agents approved by the Food and Drug Administration for patients with castration-resistant metastatic disease. Each drug works in a different way to block hormones. Abiraterone and enzalutamide are both highly effective drugs in blocking hormones in men with CRPC. Abiraterone has recently received FDA approval for patients who have not received chemotherapy, such those patients eligible for this study.

Click here for more information from the National Cancer Institute.

Principal Investigator(s)
George Kovach

Clinical Trial Categories

  • Cancer
  • Prostate Cancer
Sponsor(s)
Alliance for Clinical Trials in Oncology
Contact
Kim Turner, R.N. at 563-421-1908
or turnerk@genesishealth.com

Location

  • Cancer Care Institute
    1351 West Central Park
    Pavilion 1, 1st Floor
    Davenport, IA 52804
    Main: 563-421-1900
    Alternate: 800-446-6088
    Fax: 563-421-1938

Contact Us

For more information about our research program and IRB, please contact:

Research Support Office
563-421-7955

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