This research is being done because there currently is no generally agreed upon treatment to prevent melanoma, a type of skin cancer, from coming back. We hope to find a more effective and long lasting treatment for patients with melanoma.
The purpose of this study is to find out if a biological agent, called GM-CSF, stops or delays melanoma from returning. In patients with a cell marker called HLA-A2, we hope to find out if GM-CSF plus a vaccine made against tumor protein fragments stops or delays the skin cancer from returning better than GM-CSF alone.
No treatment (GM-CSF placebo and/or vaccine placebo) is considered the standard treatment for this study.