Chemo Drugs

Allopurinol (Zyloprim)

What Does It Look Like?

Tablet

How Is It Given?

Oral (by mouth)

Why Am I Taking It?

To reduce elevated uric acid levels in the blood caused by cell destruction from chemotherapy. It is also used to prevent kidney stones.

What Side Effects May Occur?

• Allopurinol may cause drowsiness especially during the first few days. Use caution if engaging in activities that require alertness.
• Stomach upset, nausea, diarrhea, vomiting, and headache may also occur as your body adjusts to the medication.
• Notify your doctor if you develop yellowing of the eyes or skin, sore throat, easy bruising or bleeding, muscle aches, numbness or tingling of legs and arms, fatigue, rash, or itchy skin.

How Do I Take This Medication?

• This drug is best taken with food or milk to prevent an upset stomach. It is advisable to drink a full glass of water with each dose and to drink at least 8 glasses (8 ounces each) of water a day while taking this medicine to prevent the formation of kidney stones.
• Large doses of vitamin C should be avoided while taking this medicine as it can increase the risk of kidney stone formation.

What If I Miss A Dose?

If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Storage:

Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom.