Chemo Drugs

Mitoxantrone (Novantrone)

What Does It Look Like?

Blue-green liquid

How Is It Given?

Intravenous (vein)

Why Am I Taking It?

Mitoxantrone is an anti-cancer drug that stops cell growth and division. This drug is usually used to treat cancers of the breast, lymphomas, leukemia, and ovarian.

What Side Effects May Occur?

You may experience some, all, or none of those listed. Most side effects do not last long. Tell the doctor or nurse about any that you notice. The information here does not include all possible side effects; others may occur. Please report any problems to your doctor.

Low Blood Counts

• A drop in blood cell counts, especially white blood cells, occurs about 10-14 days after treatment.
• Call your doctor for signs of infection or bleeding.
• Avoid situations in which you may be exposed to people with infections.
• Your blood will be drawn occasionally to check your blood counts while your are receiving this drug.

Nausea, Vomiting, Appetite Loss

• Usually mild nausea or vomiting. Anti-nausea drugs can be ordered to control these symptoms if they occur.

Hair Loss

• Rarely causes hair loss.

Skin Irritation

• If medication does not go into vein a Bluish discoloration may occur along the vein.
• The whites of your eyes may have a temporary blue discoloration which is harmless.

Kidney Function

• Your urine may be temporarily blue-green. This is harmless.

Special Notes

• Heart damage may occur with high dose of this drug. A total lifetime dose has been determined and will not be exceeded. (Call your doctor if you notice your feet swelling or shortness of breath). This is more likely if you have or are receiving other drugs which affect the heart.
• Changes in your menstrual cycle or sperm count may occur. Discuss birth control measures with your doctor as it is not advisable to conceive or to father children while taking this drug.