Chemo Drugs
Procarbazine (Matulane)
What Does It Look Like?
Yellow capsule
How Is It Given?
Oral (mouth)
Why Am I Taking It?
Procarbazine is an anti-cancer drug that stops cell growth. This drug is used to treat Hodgkin's disease and in the treatment of some brain tumors.
What Side Effects May Occur?
You may experience some, all, or none of those listed. Most side effects do not last long. Tell the doctor or nurse about any that you notice. The information here does not include all possible side effects; others may occur. Please report any problems to your doctor.
Low Blood Counts
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A drop in blood cell counts, especially white blood cells and platelets, occurs within 4-6 weeks after treatment. Your blood will be drawn occasionally to check your blood counts.
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Tell your doctor about any signs of infection or bleeding.
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Avoid situations where you may be exposed to people with infections.
Nausea, Vomiting
Special Notes
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Certain foods, drinks, and other drugs may cause serious reactions when taken during Procarbazine therapy and for 14 days after you have finished the drug.
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Do not take:
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Alcoholic beverages.
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Foods containing tyramine (common in foods that are aged to increase flavor) - some cheeses, pickled herring, bananas, sour cream, yogurt, chicken liver, canned figs, raisins, yeast extracts, or meats prepared with tenderizers.
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Decongestants, bronchodilators, antidepressants, sedative type of drugs, cold and cough medicines, appetite control, or stay awake products.
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Do not take any other drugs without asking your doctor.
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Changes in your menstrual cycle or sperm count may occur. Discuss birth control measures with your doctor as it is not advisable to conceive or to father children while taking this drug.
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Check with your doctor or emergency room immediately if you have severe headache, stiff neck, chest pain, or rapid heartbeat. These may be symptoms of a serious high blood pressure reaction.
