Breast Cancer: CALGB 49907 (Hematology Oncology Associates)

CALGB 49907 A Randomized Trial of Adjuvant Chemotherapy With Standard Regimens Cyclophosphamide, Methotrexate and Fluorouracil – (CMF) of doxorubicin and Cyclophosphamide – (AC), Versus Capecitabine in Women 65 Years and Older With Node Positive or High-Risk Node-Negative Breast Cancer.


To compare the effectiveness of standard chemotherapy regimens (Cyclophosphamide, Methotrexate and Fluorouracil [CMF] or Doxorubicin and Cyclophosphamide [AC]) with single agent Capecitabine with respect to disease-free survival in women 65 years and older with local and regional breast cancer.

Principal Investigator(s)
Shobha Chitneni

Clinical Trial Categories

  • Cancer
  • Breast Cancer
Cancer and Leukemia Group B
Katy D'Aprile, RN, BSN at 563-355-7733


  • University of Iowa Hospital & Clinics, Cancer Center of the Quad Cities
    1351 East Kimberly Road
    Suite 100
    Bettendorf, IA 52722

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