Multiple Myeloma: E3A06 (Hematology Oncology Associates)

ECOG-ACRIN E3A06: Randomized Phase III Trial of Lenalidomide Versus Observation Alone in Patients with Asymptomatic High-Risk Smoldering Multiple Myeloma


The purpose of this study is to find out what effects (good and bad) the use of the drug lenalidomide has on patients with asymptomatic high-risk smoldering multiple myeloma, and to compare this with patients that receive no therapy.

This research study is being done because there is no current therapy proven to benefit patients with high-risk asymptomatic myeloma, a type of blood cell cancer that has not yet damaged body tissue and organs to the point where symptoms are noticeable. Currently, these patients are not treated unless their disease progresses to symptomatic myeloma.

Click here for more information from the National Cancer Institute.

Principal Investigator(s)
Shobha Chitneni

Clinical Trial Categories

  • Cancer
  • Multiple Myeloma
Eastern Cooperative Oncology Group
Katy D'Aprile, RN, BSN at 563-355-7733


  • University of Iowa Hospital & Clinics, Cancer Center of the Quad Cities
    1351 East Kimberly Road
    Suite 100
    Bettendorf, IA 52722

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