Breast Cancer: Alliance A011401 (Iowa Cancer Specialists)

Alliance A011401: Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer


This study is being done to see if losing weight may help prevent breast cancer from coming back (recurring).

Previous studies have found that women who are overweight or obese when their breast cancer is found (diagnosed) have a greater risk of their breast cancer recurring, as compared to women who were thinner when their cancer was diagnosed. At this time we do not know whether or not losing weight will reduce the risk of breast cancer returning. 

This study seeks to determine whether or not the higher risk for breast cancer recurrence in women who are overweight or obese when they are diagnosed with breast cancer could be reduced or eliminated if weight is lost. We do not know how much weight would need to be lost to lower the risk of breast cancer recurrence, or whether this strategy would work for all women. This study will help to show us whether weight loss programs should be a part of breast cancer treatment.

Principal Investigator(s)
George Kovach

Clinical Trial Categories

  • Breast Cancer
Alliance for Clinical Trials in Oncology
Kim Turner, R.N. at 563-421-1908


  • Genesis Medical Center, West Central Park
    1401 West Central Park Avenue
    Davenport, IA 52804
    Main: 563-421-1000

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