Iliac Compression Study

Clinical and Imaging Predictors of Significant Iliac Compression using Intravascular Ultrasound as Gold Standard (Iliac Compression)


To examine whether or not clinical parameters and indicators from computed tomography (CT) imaging can be used to effectively predict the presence of significant iliac compression.

Iliac compression is frequently encountered on computed tomography (CT) scan of the pelvis. This compression is partial in most instances. Quite often it is difficult to determine whether this compression is functionally significant and
is responsible for patients’ symptoms of lower extremity pain and swelling.

The gold standard to define the degree of severity of iliac compression is the intravascular ultrasound (IVUS). Compression is considered significant if it generally exceeds 50% of the normal reference surface area by IVUS. The presence of more than 50% surface area reduction by IVUS coupled with the presence of collaterals by venography and the presence of fibrotic rings and/or spurs by IVUS are likely to correlate with the patient symptoms and the improvement in these symptoms post treatment. However venography and IVUS are an invasive procedures. In this study we are evaluating non-invasive methods to determine the predictors of significant iliac compression using clinical and CT parameters.


Principal Investigator(s)
Nicholas Shammas

Clinical Trial Categories

  • Cardiac Research
Midwest Cardiovascular Research Foundation at 563-324-2828


  • Genesis Medical Center, East Rusholme Street
    1227 East Rusholme Street
    Davenport, IA 52803
    Main: 563-421-1000

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