Ryan Perumpail, MD - Genesis Health System

Ryan Perumpail, MD

563-421-8900 Call for an Appointment

I am passionate about using minimally-invasive endoscopic approaches to diagnose, stage, treat, and palliate digestive diseases, particularly bile duct and pancreatic conditions, large colon polyps, and Barrett’s esophagus-related dysplasia and early cancer lesions. Endoscopy provides valuable information for patient management and may provide a surgery-sparing alternative for the appropriate patient.

My philosophy of care is to leverage the most cutting-edge endoscopic procedural techniques to improve the gastrointestinal health and well-being of my community.


Office Hours

Sunday: Closed
Monday: 8:00 AM - 5:00 PM
Tuesday: 8:00 AM - 5:00 PM
Wednesday: 8:00 AM - 5:00 PM
Thursday: 8:00 AM - 5:00 PM
Friday: 8:00 AM - 5:00 PM
Saturday: Closed


Year began practicing:
Year joined staff:


  • Gastroenterology

Areas Of Interest

My clinical interests involve the application of advanced endoscopic techniques and interventions to diagnose, stage, treat, and palliate a broad range of benign and malignant gastrointestinal conditions. Specifically, I am interested in the application of endoscopic ultrasound (EUS) with fine needle aspiration and biopsy for gastrointestinal and pancreaticobiliary tumors, EUS for celiac plexus neurolysis to address pancreatic cancer-related pain, therapeutic EUS for pancreatic pseudocyst drainage and necrosectomy, therapeutic EUS for biliary drainage, therapeutic endoscopic retrograde cholangiopancreatography (ERCP) including cholangioscopy-guided techniques for common bile duct stones and pancreaticobiliary tumors, complex stricture dilation and endotherapy, endoscopic mucosal resection (EMR) for large colon polyps and foregut lesions, endoscopic submucosal dissection (ESD), complex polypectomy, tumor ablation, endoscopic treatment of Barrett’s esophagus with mucosal resection and radiofrequency ablation and cryoablation, endoluminal stenting for malignant gastrointestinal strictures, endoscopic myotomy for Zenker’s diverticulum, esophageal per-oral endoscopic myotomy for achalasia and esophageal motility disorders, gastric per-oral endoscopic myotomy for gastroparesis, and transoral gastric outlet reduction to address weight regain after gastric bypass surgery, and endoscopic suturing.

I enjoy spending time with my family, playing and watching basketball, hiking, traveling, and mentoring the next generation of physicians.

Education & Training


Northwestern University, Feinberg School of Medicine, MD
Northwestern University, Undergraduate Degree


University of California Los Angeles (UCLA), Gastroenterology and Hepatology
Beth Israel Medical Center and Harvard Medical School, Therapeutic Endoscopy (Interventional Gastroenterology)

Awards & Certifications

Honors, Awards, etc.

  • Alpha Omega Alpha Honor Medical Society
  • Phi Beta Kappa Summa Cum Laude Digestive Disease Week (DDW)
  • Poster of Distinction American Association for the Study of Liver Diseases (AASLD)
  • Poster of Distinction Yale/Stanford Johnson & Johnson
  • Global Health Scholars Travel Grant Hoyt Scholarship: Recognizes leadership, community involvement, and academic performance among medical students
  • McGraw Hill-Lange Medical Student Award: Recognizes top two medical students based on academic performance

Board Certification

  • Internal Medicine, 2015
  • Gastroenterology, 2020

Professional Positions

Professional Memberships

  • I serve on the Clinical Guidelines Committee as well as the Trainee and Early Career Committee for the American Gastroenterological Association (AGA).
  • I serve on the History and Archives Committee for the American Society for Gastrointestinal Endoscopy (ASGE).
  • I am a member of the American College of Gastroenterology (ACG) and American College of Physicians (ACP).